微生物多样性测序三代全长扩增子宏基因组测序宏基因组Binning分析宏基因组抗性基因测序宏基因组元素循环测序高宿主污染去除宏基因组项目HiC-Meta宏基因组三代全长宏基因组宏转录组差异表达测序环境宏病毒组测序医学宏病毒组测序动植物基因组Denovo测序细菌基因组测序项目真菌基因组测序项目病毒基因组测序项目简化基因组遗传图谱简化基因组GWAS测序BSA混池测序基因组SSR开发基因组重测序真核有参转录组测序真核无参转录组测序原核链特异性转录组测序全长转录组(有参_无参)测序LncRNA测序Small RNA测序互作转录组测序比较转录组测序Meta-Barcoding(eDNA)技术研究5R 16S rRNA微生物多样性绝对定量 Spike-in种质资源数字化解决方案转座子插入测序(Tn-seq)PlantArray植物生理组平台UMI-RNA-seq技术染色体级别基因组组装Hi-C建库叶绿体、线粒体基因组测序高通量土壤生物检测Astral蛋白质组学植物单细胞核转录组动物单细胞核转录组动物单细胞转录组单菌株单细菌转录组人肠道单细菌转录组10x单细胞转录组单细胞转录组(SMART)测序靶向代谢组分析非靶向代谢组分析ATAC-seqChip-seqRip-seq全基因组甲基化分析扩增子引物列表资料下载送样指南客户文章列表
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产品介绍

微生物群落的结构、基因功能及代谢机理是微生物生态学的研究热点。由于微生物的活动,使得微生物群落所在的环境样本及生物学样本具有生物活性功能,推动着自然界中重要的物质循环。因此,很多科学家在研究此类样本时更关注功能基因簇的序列特征,以及特殊功能基因(如抗性基因、毒力基因等)的种类及丰度等。

凌恩生物的宏基因组抗性基因检测方案应运而出。通过宏基因组技术,高效准确的对环境样本中抗生素抗性基因进行定性定量。



技术流程

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送样要求


样品类型

                                取样材料或者DNA

样品浓度

                                ≧30ng/ul

样品总量

                                ≧2ug




分析示例


宏基因组抗性基因检测.png



部分凌恩客户文章

发表时间文章标题杂志名影响因子合作单位
2023Metagenomics insights into the effects of lactic acid bacteria inoculation on
the biological reduction of antibiotic resistance genes in alfalfa silage
Journal of Hazardous Materials13.6兰州大学
2023Unraveling antibiotic resistomes associated with bacterial and viral communities in intertidal mudflat aquaculture areaJournal of Hazardous Materials13.6河海大学
2022Deciphering the mechanisms shaping the plastisphere antibiotic resistome on riverine microplasticsWater Research13.4中国东华大学
2023Rare resistome rather than core resistome exhibited higher diversity and risk along the Yangtze RiverWater Research12.8中国科学院武汉植物园
2022Para-chloro-meta-xylenol reshaped the fates of antibiotic resistance genes during sludge fermentation: Insights of cell membrane permeability, bacterial structure and biological pathwaysScience of the Total Environment10.753河海大学
2022Tidal flat aquaculture pollution governs sedimentary antibiotic resistance gene profiles but not bacterial community based on metagenomic dataScience of the Total Environment10.753河海大学
2023Surfactant aggravated the antibiotic's stress on antibiotic resistance genesproliferation by altering antibiotic solubilization and microbial traits insludge anaerobic fermentation
Science of the Total Environment9.8河海大学
2023The diurnal fluctuation of colonic antibiotic resistome is correlated with nutrient substrates in a pig modelScience of the Total Environment9.8南京农业大学
2023Occurrence, fate and potential health risks of antibiotic resistomes in a constructed wetlands-reservoir ecosystem for drinking water source improvementScience of the Total Environment9.8盐城理工学院
2023Pathogens and antibiotic resistance genes during the landfill leachate treatment process: Occurrence, fate, and impact on groundwaterScience of the Total Environment9.8

生态环境部

南京环境科学研究所

2024Assessing intracellular and extracellular distribution of antibiotic resistance genes in the commercial organic fertilizers
Science of the Total Environment9.8南京农业大学
2024Phages in sludge from the A/O wastewater treatment process play an important role in the transmission of ARGsScience of the Total Environment9.8聊城大学
2024Health risk ranking of antibiotic resistance genes in the Yangtze RiverEnvironmental Science and Ecotechnology9.371中国科学院武汉植物园
2023Hazard reduction and persistence of risk of antibiotic resistance during thermophilic composting of animal wasteJournal of Environmental Management8.91南京农业大学
2024Variations in antibiotic resistomes associated with archaeal, bacterial, and viral communities affected by integrated rice-fish farming in the paddy field ecosystemEnvironmental Research8.3中国水产科学研究
2021Metagenomic profiles of the resistome in subtropical estuaries: Co-occurrence patterns, indicative genes, and driving factorsSci Total Environ7.963广东省与香港海洋生物资源联合实验室
2023Combined virome analysis and metagenomic sequencing to reveal the viral communities and risk of virus-associated antibiotic resistance genes during compostingJournal of Hazardous Materials13.6中国热带农业科学院
2022Deciphering the response of biological nitrogen removal to gadolinium and sulfamethoxazole combined pollution: Performance, microbial community, and antibiotic resistance genesProcess Safety and Environmental Protection7.926合肥工业大学
2022Unveiling the risks and critical mechanisms of polyhexamethylene guanidine on the antibiotic resistance genes propagation during sludge fermentation processBioresour Technol7.539河海大学