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产品介绍

微生物群落的结构、基因功能及代谢机理是微生物生态学的研究热点。由于微生物的活动,使得微生物群落所在的环境样本及生物学样本具有生物活性功能,推动着自然界中重要的物质循环。因此,很多科学家在研究此类样本时更关注功能基因簇的序列特征,以及特殊功能基因(如抗性基因、毒力基因等)的种类及丰度等。

凌恩生物的宏基因组抗性基因检测方案应运而出。通过宏基因组技术,高效准确的对环境样本中抗生素抗性基因进行定性定量。



技术流程

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送样要求


样品类型

                                取样材料或者DNA

样品浓度

                                ≧30ng/ul

样品总量

                                ≧2ug




分析示例


宏基因组抗性基因检测.png



部分凌恩客户文章

发表时间文章标题杂志名影响因子合作单位
2023Metagenomics insights into the effects of lactic acid bacteria inoculation on
the biological reduction of antibiotic resistance genes in alfalfa silage
Journal of Hazardous Materials13.6兰州大学
2023Unraveling antibiotic resistomes associated with bacterial and viral communities in intertidal mudflat aquaculture areaJournal of Hazardous Materials13.6河海大学
2022Deciphering the mechanisms shaping the plastisphere antibiotic resistome on riverine microplasticsWater Research13.4中国东华大学
2023Rare resistome rather than core resistome exhibited higher diversity and risk along the Yangtze RiverWater Research12.8中国科学院武汉植物园
2022Para-chloro-meta-xylenol reshaped the fates of antibiotic resistance genes during sludge fermentation: Insights of cell membrane permeability, bacterial structure and biological pathwaysScience of the Total Environment10.753河海大学
2022Tidal flat aquaculture pollution governs sedimentary antibiotic resistance gene profiles but not bacterial community based on metagenomic dataScience of the Total Environment10.753河海大学
2023Surfactant aggravated the antibiotic's stress on antibiotic resistance genesproliferation by altering antibiotic solubilization and microbial traits insludge anaerobic fermentation
Science of the Total Environment9.8河海大学
2023The diurnal fluctuation of colonic antibiotic resistome is correlated with nutrient substrates in a pig modelScience of the Total Environment9.8南京农业大学
2023Occurrence, fate and potential health risks of antibiotic resistomes in a constructed wetlands-reservoir ecosystem for drinking water source improvementScience of the Total Environment9.8盐城理工学院
2023Pathogens and antibiotic resistance genes during the landfill leachate treatment process: Occurrence, fate, and impact on groundwaterScience of the Total Environment9.8

生态环境部

南京环境科学研究所

2024Assessing intracellular and extracellular distribution of antibiotic resistance genes in the commercial organic fertilizers
Science of the Total Environment9.8南京农业大学
2024Phages in sludge from the A/O wastewater treatment process play an important role in the transmission of ARGsScience of the Total Environment9.8聊城大学
2024Health risk ranking of antibiotic resistance genes in the Yangtze RiverEnvironmental Science and Ecotechnology9.371中国科学院武汉植物园
2023Hazard reduction and persistence of risk of antibiotic resistance during thermophilic composting of animal wasteJournal of Environmental Management8.91南京农业大学
2024Variations in antibiotic resistomes associated with archaeal, bacterial, and viral communities affected by integrated rice-fish farming in the paddy field ecosystemEnvironmental Research8.3中国水产科学研究
2021Metagenomic profiles of the resistome in subtropical estuaries: Co-occurrence patterns, indicative genes, and driving factorsSci Total Environ7.963广东省与香港海洋生物资源联合实验室
2023Combined virome analysis and metagenomic sequencing to reveal the viral communities and risk of virus-associated antibiotic resistance genes during compostingJournal of Hazardous Materials13.6中国热带农业科学院
2022Deciphering the response of biological nitrogen removal to gadolinium and sulfamethoxazole combined pollution: Performance, microbial community, and antibiotic resistance genesProcess Safety and Environmental Protection7.926合肥工业大学
2022Unveiling the risks and critical mechanisms of polyhexamethylene guanidine on the antibiotic resistance genes propagation during sludge fermentation processBioresour Technol7.539河海大学