微生物群落的结构、基因功能及代谢机理是微生物生态学的研究热点。由于微生物的活动，使得微生物群落所在的环境样本及生物学样本具有生物活性功能，推动着自然界中重要的物质循环。因此，很多科学家在研究此类样本时更关注功能基因簇的序列特征，以及特殊功能基因（如抗性基因、毒力基因等）的种类及丰度等。

凌恩生物的宏基因组抗性基因检测方案应运而出。通过宏基因组技术，高效准确的对环境样本中抗生素抗性基因进行定性定量。

1. Tidal flat aquaculture pollution governs sedimentary antibiotic resistance gene profiles but not bacterial community based on metagenomic data. Science of the Total Environment (IF=10.753),2022

2. Para-chloro-meta-xylenol reshaped the fates of antibiotic resistance genes during sludge fermentation: Insights of cell membrane permeability, bacterial structure and biological pathways.   Science of the Total Environment (IF=10.753),2022

3. Deciphering the mechanisms shaping the plastisphere antibiotic resistome on riverine microplastics. Water Research (IF=9.13),2022

4. Metagenomic profiles of the resistome in subtropical estuaries: Co-occurrence patterns, indicative genes, and driving factors. Sci Total Environ (IF=7.963),2021

5. Deciphering the response of biological nitrogen removal to gadolinium and sulfamethoxazole combined pollution: Performance, microbial community, and antibiotic resistance genes. Process Safety and Environmental Protection(IF=7.926), 2022

6. Unveiling the risks and critical mechanisms of polyhexamethylene guanidine on the antibiotic resistance genes propagation during sludge fermentation process. Bioresour Technol(IF=7.539), 2022

7. The changes in antibiotic resistance genes during 86 years of the soil ripening process without anthropogenic activities.Chemosphere(IF=5.778), 2020

8. Deterministic assembly process dominates bacterial antibiotic resistome in wastewater effluents receiving river. Environmental Science and Pollution Research(IF=5.19), 2022