基因组de novo测序，又名从头测序，指不需要任何参考基因组信息即可对某个物种的基因组进行测序，利用生物信息学分析方法进行基因组的拼接、组装，获得该物种的基因组序列图谱，从而推进该物种的后续研究。
凌恩生物整合多种优势技术及信息分析平台，涵盖illumina，Pacbio, Nanopore等多种测序平台，10x Genomics长片段读取技术, Bionano单分子光学图谱技术，Dovetail TM Hi-C及Dovetail TM Chicago三维基因组技术，NRGene基因组组装算法等，为广大科研工作者提供多种前沿动植物基因组研究技术。
高难度基因组解决方案：技术平台联手以色列NRGene，实力挑战超大、超复杂、高重复、多倍体及高杂合基因组。
多种技术组合方案：满足您不同层次分析要求。可实现完整的基因组组装，为遗传学发现、性状发现、关联研究、基因组选择与基因编辑等提供坚实的基础框架。
实力雄厚，经验丰富。凌恩核心团队负责人，均10年以上基因组研究领域工作经验。已完成复杂高难度基因组项目数十项，具有丰富的基因组组装及深度挖掘项目经验。
组织 | 动植物≥2g，血液样本>1mL |
纯度 | OD260/280:1.8-2.0 |
| 项目经验：动物基因组 |
物种中文名
| 拉丁学名
| 基因组大小
| 发表期刊名 | 发布年份 |
| 灰飞虱 | Laodelphax striatellus
| 510Mb | Genomics | 2022
|
秀丽隐杆线虫
| Caenorhabditis elegans | 100Mb | Environ. Sci. Technol.
| 2022 |
| 灰飞虱 | Laodelphax striatellus (Fallén)
| 510Mb | LWT
| 2022 |
泥虾
| Upogebia major
| -
| Research Square
| 2021 |
红条毛肤石鳖
| Acanthochitona rubrolineatus
| - | Research Square
| 2021 |
石斑鱼
| Epinephelus moara♀ × E. lanceolatus♂
| 1G | Aquaculture
| 2021 |
棉铃虫群体进化
| Bacillus thuringiensis
| 6Mb | Pest Management Science
| 2021 |
烟粉虱
| Bemisia tabaci | 620Mb | Pest Management Science
| 2021 |
猪
| Sus scrofa
| 2.5G | PLoS Genet
| 2021 |
小鼠胚胎干细胞
| Mus musculus
| 2.7G | Stem Cells and DevelopmentVol
| 2021 |
大口黑鲈
| Micropterus salmoides
| 960Mb | Molecular Ecology
| 2020 |
大鲵
| Andrias davidianus
| - | BMC Genomics
| 2019
|
| 灰飞虱 | Laodelphax striatellus
| 510G | Journal of Economic Entomology
| 2019 |
山羊
| Goat Latin
| 3G | 3 Biotech
| 2019 |
东方斑鸠
| Streptopelia orientalis
| -
| Conservation Genetics Resources
| 2019 |
日本血吸虫
| Nipponacmea schrenckii
| - | Conservation Genetics Resources
| 2019 |
鳜鱼
| Siniperca chuatsi
| 720Mb | BMC genomics | 2017 |
对虾
| Marsupenaeus japonicus
| 1.5G
| Mol Genet Genomics
| 2016
|
大菱鲆
| Scophthalmus maximus L.
| 540Mb | PLoS One
| 2015
|
牙鲆
| Paralichthys olivaceus
| 640Mb | DNA research
| 2015
|
欧洲鳗鲡&美洲鳗
| Anguilla anguilla & A. rostrata
| 980Mb | Molecular Ecology
| 2014
|
三刺鱼
| Gasterosteus aculeatus
| 470Mb | BMC genomics | 2014 |
项目经验：植物基因组
|
物种中文名
| 拉丁学名 | 基因组大小 | 发表期刊名 | 发布年份 |
菜用大豆
| Glycine max L.
| 1G
| Horticulture Research
| 2022 |
梨
| Pyrus spp
| 510Mb | Horticulture Research | 2022 |
黑杨
| Populus deltoids
| 390Mb | BMC Genomics | 2022 |
梅花
| Prunus mume
| 230Mb | Frontiers in Plant Science
| 2022 |
拟南芥
| Arabidopsis thaliana
| 120Mb | Molecules
| 2022 |
绿豆
| Vigna radiata L.
| 460Mb | Agronomy Journal
| 2022 |
番茄
| Solanum lycopersicum
| 830Mb | Journal of Experimental Botany
| 2022 |
东乡野生稻
| Oryza rufipogon Griff.
| 460Mb | Rice Science
| 2022 |
盐杨科物种
| Chosenia arbutifolia
| 340Mb | GigaScience
| 2022 |
粳稻
| Neotrypaea japonica
| - | Research Square | 2021 |
| 瓠瓜 | Lagenaria siceraria | 300Mb | The Plant Journal | 2021 |
茄子
| Solanum melongena L.
| 830Mb | Molecular Ecology Resource | 2021 |
葫芦
| Lagenaria siceraria (Mol.) Standl.
| 300Mb | Frontiers in Plant Science | 2021 |
玉米
| Zea mays L | 2.2G | Front Plant Sci | 2021 |
番茄
| Solanum lycopersicum | 830Mb | iScience
| 2021 |
津田萝卜
| Brassica rapa subsp. rapa | 350Mb | International Journal of Molecular Sciences
| 2021 |
三角杨
| Populus deltoides
| 420Mb | Journal of Heredity | 2021 |
| 豇豆 | Vigna. Unguiculata L. Walp
| 520Mb | Legume Science | 2021 |
浒苔
| Ulva prolifera | 90Mb | Chemosphere | 2021 |
豇豆
| Vigna. Unguiculata L. Walp
| 520Mb | Front Genet | 2021 |
茯苓
| Wolfiporia cocos
| 60Mb | Genomics, Proteomics & Bioinformatics | 2020 |
| 黄檀 | Dalbergia odorifera T. Chen
| 653.45Mb | Giga Science | 2020 |
沉香
| Aquilaria sinensis (Lour.) Spreng | 700Mb | Giga Science | 2020 |
甜瓜
| Cucumis melo ssp. | 440Mb | iScience
| 2020 |
葫芦
| Lagenaria siceraria | 300Mb | PLoS One
| 2020 |
陆地棉
| Gossypium barbadense and Gossypium hirsutum
| 2.2G
| NG
| 2019
|
油菜
| Brassica napus
| 1G
| Molecular Plant
| 2019 |
水稻
| Oryza sativa L.
| 400Mb | Molecular Plant
| 2019 |
大豆
| Glycine max (L.) Merr.
| 980Mb | PLOS genetics
| 2019 |
黄瓜
| Cucumis sativus L.
| 230Mb | Journal of Plant Research
| 2019 |
茄子
| Solanum melongena L.
| 830Mb | bioRxiv | 2019 |
含笑属植物
| Michelia | -
| Molecular Plant Breeding
| 2019 |
甘蓝型油菜
| Brassica napus
| 1G | BMC Genomics
| 2019 |
葡萄
| Vitis vinifera L.
| 460Mb | Scientific Reports
| 2018 |
豇豆
| Vigna unguiculata
| 520Mb | Theoretical and Applied Genetics
| 2018 |
橐吾
| Ligularia | - | J Integr Plant Biol
| 2018 |
水稻
| Oryza sativa L.
| 400Mb | Nature
| 2018 |
豇豆
| V. unguiculata L. Walp
| 520Mb | Plant Journal
| 2017 |
胡杨
| Populus euphratica
| 500Mb | Plant Journal
| 2017 |
羽扇豆
| Lupinus angustifolius L.
| 610Mb | Theor Appl Genet
| 2017 |
葫芦
| Lagenaria siceraria (Mol.) Standl.
| 300Mb | Scientia Horticulturae
| 2017 |
三七
| Panax notoginseng
| 2.7G | Mol. Plant
| 2017 |
豇豆
| V. unguiculata L. Walp
| 520Mb | Plant Biotechnology journal
| 2016 |
水稻
| Oryza sativa L. | 400Mb | Plant Breeding
| 2015
|
玉米
| Zea mays L | 2.2G
| BMC genomics | 2015 |
海带
| Saccharina japonica | 540Mb | BMC Genomics | 2015 |
| 水稻 | Oryza sativa L. | 400Mb | GigaScience
| 2014 |
| 辣椒&野生祖先 | Capsicum annuum var. glabriusculum
| 2.8G | PNAS
| 2014 |
| 瓠瓜 | Capsicum annuum var. glabriusculum
| 300Mb | Plant Journal
| 2013 |
梨树
| Pyrus bretschneideri Rehd.
| 510Mb | Genome Research | 2013 |
羽扇豆
| Lupinus angustifolius L.
| 610Mb | PLOS One | 2013 |
大豆
| Zea mays L | 980Mb | PNAS
| 2013 |
羽扇豆
| Lupinus angustifolius L.
| 610Mb | BMC Genomics
| 2012 |
| 羽扇豆 | Lupinus angustifolius L.
| 610Mb | Theoretical and Applied Genetics
| 2012 |
| 梅花 | Prunus mume
| 230Mb | Nature Communications
| 2012 |
发表时间 | 文章标题 | 杂志名 | 影响因子 | 合作单位 | 物种 |
2019 | Genomic variation in 3,010 diverse accessions of Asian cultivated rice. | Nature | 41.577 | 中国农业科学院作物科学研究所 | 水稻 |
2019 | Gossypium barbadense and Gossypium hirsutum genomes provide insights into the origin and evolution of allotetraploid cotton. | Nature genetics | 25.455 | 浙江大学 | 陆地棉和海岛棉 |
2023 | Comparative genomic analyses reveal the genetic basis of the yellow-seed trait in Brassica napus | Nature Communications | 16.6 | 西南大学 | 甘蓝型油菜 |
2019 | Chromosome-level assembly of the water buffalo genome surpasses human and goat genomes in sequence contiguity. | Nature Communications | 11.878 | 澳大利亚阿德莱德大学 | 水牛 |
2023 | A chromosome-scale genome assembly of Artemisia argyi reveals unbiased subgenome evolution and key contributions of gene duplication to volatile | Plant Communications | 10.5 | 北京协和医院 | 艾蒿 |
2024 | Chromosome-level genome assembly and annotation of rare and endangered tropical bivalve, Tridacna crocea | Scientific Data | 9.8 | 中国科学院 | 大黄砗磲 |
2022 | The whole-genome assembly of an endangered Salicaceae species: Chosenia arbutifolia (Pall.) A. Skv. | GigaScience | 7.463 | 江苏省国家林业研究院 | 盐杨 |
2022 | Genome sequencing and population resequencing provide insights into the genetic basis of domestication and diversity of vegetable soybean | Horticulture Research | 7.291 | 浙江省农科院 | 菜用大豆 |
2020 | The Wolfiporia cocos Genome and Transcriptome Shed Light on the Forma‐ tion of Its Edible and Medicinal Sclerotium | Genomics, Proteomics & Bioinformatics | 7.051 | 中国中医科学院中药研究所 | 茯苓 |
2024 | Multigenerational effects and mutagenicity of three flame retardants on germ cells in Caenorhabditis elegans | ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY | 6.8 | 中国科学院合肥物质科学研究院 | 秀丽隐杆线虫 |
2021 | Long-read genome assembly and genetic architecture of fruit shape in the bottle gourd | The Plant Journal | 6.417 | 浙江省农业科学院蔬菜研究所 | 瓠瓜 |
2021 | A high-quality genome assembly of the eggplant provides insights into the molecular basis of disease resistance and chlorogenic acid synthesis | Molecular Ecology Resource | 6.286 | 广西农业科学院蔬菜研究所 | 茄子 |
2020 | Genome sequence of the agarwood tree Aquilaria sinensis (Lour.) Spreng: the first chromosome-level draft genome in the Thymelaeceae family | Giga Science | 5.993 | 中国农业科学院深圳农业基因组学研究所 | 沉香 |
2020 | The chromosome-level draft genome of Dalbergia odorifera | GigaScience | 5.993 | 中国科学院热带林业研究所 | 黄檀 |
2020 | Chromosome‐level genome assembly for the largemouth bass Micropterus salmoides provides insights into adaptation to fresh and brackish water | Molecular Ecology | 5.855 | 中国科学院大学 | 大口黑鲈 |
2021 | Integrated effects of Ulva prolifera bloom and decay on nutrients inventory and cycling in marginal sea of China | Chemosphere | 5.778 | 中国海洋大学 | 浒苔 |
