微生物多样性测序三代全长扩增子宏基因组测序宏基因组Binning分析宏基因组抗性基因测序宏基因组元素循环测序高宿主污染去除宏基因组项目HiC-Meta宏基因组三代全长宏基因组宏转录组差异表达测序环境宏病毒组测序医学宏病毒组测序动植物基因组Denovo测序细菌基因组测序项目真菌基因组测序项目病毒基因组测序项目简化基因组遗传图谱简化基因组GWAS测序BSA混池测序基因组SSR开发基因组重测序真核有参转录组测序真核无参转录组测序原核链特异性转录组测序全长转录组(有参_无参)测序LncRNA测序Small RNA测序互作转录组测序比较转录组测序Meta-Barcoding(eDNA)技术研究5R 16S rRNA微生物多样性绝对定量 Spike-in种质资源数字化解决方案转座子插入测序(Tn-seq)PlantArray植物生理组平台UMI-RNA-seq技术染色体级别基因组组装Hi-C建库叶绿体、线粒体基因组测序高通量土壤生物检测Astral蛋白质组学植物单细胞核转录组动物单细胞核转录组动物单细胞转录组单菌株单细菌转录组人肠道单细菌转录组10x单细胞转录组单细胞转录组(SMART)测序靶向代谢组分析非靶向代谢组分析ATAC-seqChip-seqRip-seq全基因组甲基化分析扩增子引物列表资料下载送样指南客户文章列表
021-31021022 ;13032137192

产品介绍

在高等生物细胞内除了细胞核遗传外,细胞质遗传也是重要的研究方向。细胞质中主要的遗传物质的载体是线粒体和叶绿体。利用高通量测序技术对动植物线粒体基因组植物叶绿体基因组进行测序组装,突破传统mt/cpDNA分离提纯的实验壁垒,可直接利用组织总DNA获得线粒体/叶绿体基因组,对序列信息进行深入解析,通过比较基因组分析获得物种分类、系统进化、地理谱系遗传等信息

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凌恩生物自主研发的Enrichment富集技术,可降低核DNA污染,将总DNA中靶细胞器基因组比例提升。专业生物信息团队,提供人工基因注释矫正,满足NCBI数据库上传要求,高质量结果交付,助力高水平研究。

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技术流程

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项目经验

细胞器基因组-2021.01-1.jpg


技术优势

1. 提供mtDNAcpDNA富集抽提服务:自主研发的细胞器基因组富集提取技术,高效实现高质量细胞器基因组富集。

2. 一对一的生物信息分析,人工基因注释矫正:告别在线注释平台的偏差,满足NCBI数据库上传要求,高质量结果交付,助力高水平研究。

3. 核心技术团队负责人均10年以上从业经验,项目经验丰富,提供可以个性化方案定制。

4. 已完成叶绿体线粒体基因组项目数百例,96%以上样本实现完成图水平交付。

5. 配套数据库构建服务,提升科研水准,助力高水平研究发表。



取样指南

植物叶绿体取样

植物线粒体取样

动物线粒体取样





分析示例

叶绿体、线粒体基因组测序.png




部分凌恩客户文章


叶绿体基因组

发表时间

文章标题

杂志名

影响因子

合作单位

2022

Comparative Analysis of Whole Chloroplast Genomes of Three Common Species of Echinochloa (Gramineae) in Paddy Fields

International Journal of Molecular Sciences

6.208

上海农业科学院生态环境保护研究所

2021

Comparative Chloroplast Genomes of Zosteraceae Species Provide Adaptive Evolution Insights Into Seagrass

Front Plant Sci

5.753

中国海洋大学

2021

Complete Chloroplast Genome Analysis of Two Important Medicinal Alpinia Species: Alpinia galanga and Alpinia kwangsiensis

Front Plant Sci

5.753

云南药用植物研究所云南分所

2023

Comparative Chloroplast Genomics of 21 Species in Zingiberales with Implications for Their Phylogenetic Relationships and Molecular Dating

International Journal of Molecular Sciences

5.6

广东省农业科学院环境园艺研究所

2022

Comparative Analysis of Whole Chloroplast Genomes of Three Common Species of Echinochloa (Gramineae) in Paddy Fields

Int J Mol Sci

5.6

上海农业科学院生态环境保护研究所

2022

Comparative analysis of complete chloroplast genome of ethnodrug Aconitum episcopale and insight into its phylogenetic relationships

Scientifc Reports |

4.996

华东科技大学

2022

Complete Chloroplast Genomes and Comparative Analyses of Three Ornamental Impatiens Species

Frontiers in genetics

4.772

西南林业大学

2022

Chloroplast Genomes of Genus Tilia: Comparative Genomics and Molecular Evolution

Frontiers in Genetics

4.772

南京植物园

2022

Comparative Analysis of the Chloroplast Genome for Aconitum Species: Genome Structure and Phylogenetic Relationships

Frontiers in Genetics

4.772

华东科技大学

2024

Comparative chloroplast genomics, phylogenetic relationships and molecular markers development of Aglaonema commutatum and seven green cultivars of Aglaonema

Scientifc Reports

4.6

广东省农业科学院环境园艺研究所

2020

Comparative Analyses of Five Complete Chloroplast Genomes from the Genus Pterocarpus (Fabacaeae)

International Journal of Molecular Sciences

4.556

中国林业科学研究院 热带林业研究所树木遗传育种国家重点实验室

2024

Thirteen complete chloroplast genomes of the costaceae family: insights into genome structure, selective pressure and phylogenetic relationships

BMC Genomics

4.4

广东省农业科学院

2024

Complete chloroplast genome and comparison of herbicides toxicity on Aeschynomene indica (Leguminosae) in upland direct-seeding paddy field

BMC Genetics

4.4

上海科学院生态环境保护研究所

2021

Molecular evolution of chloroplast genomes in subfamily Zingiberoideae (Zingiberaceae

BMC Plant Biol

4.215

广东省农业科学院环境园艺研究所

2023

Comparison of Biological and Genetic Characteristics between Two Most Common Broad-Leaved Weeds in Paddy Fields:   Ammannia arenaria   and   A. multiflora   (Lythraceae)

Biology (Basel)

4.2

上海市农业科学院生态环境保护研究所

2020

Evolutionary patterns of plastome uncover diploid-polyploid maternal rela- tionships in Triticeae

Molecular Phylogenetics and Evolution

3.992

四川农业大学小麦研究所

2022

Comparative chloroplast genomes and phylogenetic relationships of Aglaonema modestum and five variegated cultivars of Aglaonema

PLoS One

3.7

广东省农业科学院研究所

2021

Comparative chloroplast genomes: insights into the evolution of the chloroplast genome of Camellia sinensis and the phylogeny of Camellia

BMC Genomics

3.594

五邑大学

2021

The complete chloroplast genome of Stauntonia chinensis and compared analysis revealed adaptive evolution of subfamily Lardizabaloideae species in China

BMC Genomics

3.594

九江大学药学院

2020

Comparative chloroplast genomics of the genus Taxodium

BMC Genomics

3.501

江苏省中国科学院植物研究所

线粒体基因组

发表时间

文章标题

杂志名

影响因子

合作单位

2021

The memory of neuronal mitochondrial stress is inherited transgenerationally via elevated mitochondrial DNA levels

Nature Cell Biology

28.213

中国科学院遗传与发育生物学研究所

2019

Mitochondrial variation in small brown planthoppers linked to multiple traits and likely reflecting a complex evolutionary trajectory

Molecular Ecology

5.855

南京农业大学

2021

Characterization of the complete mitochondrial genome of the many-lined sun skink (Eutropis multifasciata) and comparison with other Scincomorpha species

Genomics

5.736

南京师范大学

2023

The Complete Mitochondrial Genome of Pennella sp. Parasitizing Thunnus albacares

Front Cell Infect Microbiol

5.7

中国水产科学院

2023

The Complete Mitochondrial Genome and Phylogenetic Analysis of the Freshwater Shellfish Novaculina chinensis (Bivalvia: Pharidae)

International Journal of Molecular Sciences

5.6

福建师范大学

2023

Complete Mitochondrial Genome Sequence and Phylogenetic Analysis of Procambarus clarkii and Cambaroides dauricus from China

International Journal of Molecular Sciences

5.6

中国水产科学研究院

2023

A Comparative Analysis of Selection Pressures Suffered by Mitochondrial Genomes in Two Planthopper Species with Divergent Climate Distributions

Int J Mol Sci

5.6

南京农业大学

2023

The garden asparagus (Asparagus officinalis L.) mitochondrial genome revealed rich sequence variation throughout whole sequencing data

Frontiers in Plant Science

5.6

南昌师范学院

2022

Complete mitochondrial genome sequencing and identification of candidate genes responsible for C5-type cytoplasmic male sterility in cabbage ( B. oleracea   var.   capitata )

Frontiers in Microbiology

5.2

北京市农林科学院北京市蔬菜研究中心

2023

Comparative Mitogenome Analyses Uncover Mitogenome Features and Phylogenetic Implications of the Parrotfishes (Perciformes: Scaridae)

Biology-Basel

5.168

中国水产科学研究院南海水产研究所

2022

Mitogenomes Provide Insights Into the Evolution of Thoracotremata (Brachyura: Eubrachyura)

Frontiers in Marine Science

5.084

中科院海洋所

2022

Organellar genome comparisons of Sargassum polycystum and S. plagiophyllum (Fucales, Phaeophyceae) with other Sargassum species

BMC Genomics

4.547

中国科学院海洋研究所

2022

Comparative analysis of mitochondrial genomes reveals marine adaptation in seagrasses

BMC Genomics

4.547

中国海洋大学

2023

Adaptive evolution characteristics of mitochondrial genomes in genus Aparapotamon (Brachyura, Potamidae) of freshwater crabs

BMC Genomics

4.547

南昌大学基础医学院

2020

Genome‑wide analysis of mRNA and lncRNA expression and mitochondrial genome sequencing provide insights into the mechanisms underlying a novel cytoplasmic male sterility system, BVRC‑CMS96, in Brassica rapa

Theoretical and Applied Genetics

4.439

北京农林科学院蔬菜研究中心(BVRC)

2022

The cotton mitochondrial chimeric gene orf610a causes male sterility by disturbing the dynamic balance of ATP synthesis and ROS burst

The Crop Journal

4.407

郑州大学

2023

Comparative Mitogenome Analyses Uncover Mitogenome
Features and Phylogenetic Implications of the Reef Fish Family
Holocentridae (Holocentriformes)

Biology

4.2

中国水产科学研究院南海水产研究所

2021

Complete Mitochondrial Genome Sequence and Identification of a Candidate Gene Responsible for Cytoplasmic Male Sterility in Celery ( Apium graveolens L.)

International Journal of Molecular Sciences

4.183

中国农业大学

2023

The Complete Mitochondrial Genome of the Hermit Crab
Diogenes edwardsii (Anomura: Diogenidae) and Phylogenetic
Relationships within Infraorder Anomura

Genes

4.141

南开大学

2023

Complete Mitochondrial Genome of Piophila casei (Diptera: Piophilidae): Genome Description and Phylogenetic Implications

Genes

4.141

贵州大学

2023

The First Complete Mitochondrial Genome of Genus Isocapnia (Plecoptera: Capniidae) and Phylogenetic Assignment of Superfamily Nemouroidea

Genes

4.141

扬州大学

2021

Mitochondrial Genomes of the Genus Claassenia (Plecoptera: Perlidae) and Phylogenetic Assignment to Subfamily Perlinae

Genes (Basel)

4.096

扬州大学 应用昆虫研究所

2022

The Complete Mitochondrial Genome of Stichopus naso (Aspidochirotida: Stichopodidae: Stichopus) and Its Phylogenetic Position

Genes

4.096

中国科学院南海海洋研究所

2019

Mitogenome types of two Lentinula edodes sensu lato populations in China

Scientific Reports

4.011

上海市农业科学院食用菌研究所

电 话:021-31021022

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邮 箱:lab@biozeron.com


上海凌恩生物科技有限公司(简称“凌恩生物”)成立于2014年,是一家从事组学科研技术服务的高新技术企业。凌恩生物拥有完备的组学测序技术平台,业务板块涉及组学研究的多个领域方向。截至2024年,凌恩生物已成立分公司或分支机构6家,服务范围辐射全球。

       以打造高品质测序及生物信息分析研发服务团队为目标,凌恩生物注重创新、时刻关注科研需求,先后研发了包括eDNA Metabarcoding,宏基因组元素循环分析,宏基因组抗性基因分析,高宿主污染去除宏基因组,宏转录组在内的微生态系列特色产品,备受广大科研工作者关注。凌恩技术团队参与的项目成果也多次发表在《Nature》《Cell》《PNAS》等国际高端学术期刊上秉持专业务实,追求卓越的理念,凌恩生物将满怀信心、迎接挑战,坚持应用新技术,研发新产品,助力科研。

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